(Gln²²)-Amyloid β-Protein (1-40)

Catalog No：GA20182-005mg CAS No.：144410-00-4 MDLNo： Brand:Glpbio purity： 特性： Purpose:The Dutch mutation (E22Q) of amyloid β-peptide aggregates more readily than the wild-type peptide and the resulting fibrils show increased neurotoxicity. The mutant peptide E22Q induced apoptosis of cerebral endothelial cells at a concentration of 25 μm, whereas WT Aβ 1-40 and the Italian mutant E22K (H-6698) showed no effect.Soluble in DMSO