(Gly²¹)-Amyloid β-Protein (1-40)

Catalog No：GA20197-005mg CAS No.：154362-03-5 MDLNo： Brand:Glpbio purity： 特性： Purpose:Contrary to β-amyloid peptides mutated at position 22 (Dutch, Italian, Arctic mutants) the Flemish mutation (A21G) shows a decreased tendency to aggregate and a reduced neurotoxicity. In the studies of Betts and Tsubuki, A21G was degraded significantly more slowly by neprilysin than the wild-type Aβ 1-40 and the E22 mutants. The relative resistance to proteolytic degradation may account for the pathogenicity of the Aβ mutant.Soluble in DMSO