Abz-Amyloid β/A4 Protein Precursor₇₇₀ (669-674)-EDDnp

Catalog No：GA20452-1mg CAS No.：1802078-43-8 MDLNo： Brand:Glpbio purity： 特性： Purpose:Intramolecularly quenched fluorescent substrate containing the ortho-aminobenzoyl (Abz) / N-(2,4-dinitrophenyl)ethylenediamine (EDDnp) groups as the donor / acceptor pair. It mimicks the wild-type (JMV2235) β-amyloid precursor protein (βAPP) sequence targeted by β-secretase BACE (β-site APP-cleaving activity). This FRET substrate is cleaved by BACE1, BACE2, and cathepsin D.Soluble in DMSO