Boc-Arg-Val-Arg-Arg-AMC

Catalog No：GA20901-100mg CAS No.：136132-77-9 MDLNo： Brand:Glpbio purity： 特性： Purpose:The fluorogenic substrate Boc-RVRR-AMC is efficiently cleaved by furin, a mammalian homolog of the yeast Kex2 endoprotease (kcat/Km approx. 4.10³ M?¹s?¹). As a calcium-dependent serine protease associated with Golgi membranes, furin is responsible for the secretory processing of precursor proteins at paired basic residues. Boc-RVRR-AMC is also cleaved by proprotein convertase 4. Stock solutions of Boc-RVRR-AMC are best prepared in DMSO.Soluble in DMSO