DABCYL-γ-Abu-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-EDANS

Catalog No：GA21360-5mg CAS No.：142988-22-5 MDLNo： Brand:Glpbio purity： 特性： Purpose:The fluorogenic peptide substrate DABCYL-Abu-HPFHLVIHT-EDANS has been developed to continuously measure the proteolytic activity of human renin (Km = 1.5 µM at physiological pH). Cleavage of the FRET substrate occurs specifically at the Leu-Val bond and corresponds to the renin cleavage site of angiotensinogen. By means of this assay as low as 30 ng/mL renin can be detected after an incubation of only 3-5 min. Enzymatic cleavage yields the EDANS-fragment M-2645.Soluble in DMSO