α-Synuclein (45-54) (human)

Catalog No：GA23997-1mg CAS No.：2243206-98-4 MDLNo： Brand:Glpbio purity： 特性： Purpose:Aggregation of α-synuclein (α-syn) into toxic fibrils is a pathogenic hallmark of Parkinson’s disease (PD). Most early onset mutations are located between residues 46-53. The sequence of α-synuclein (45-54) was used by Cheruvara and coworkers as a template for a peptide library. The authors isolated a 10-residue peptide antagonist that potently inhibits α-synuclein aggregation and associated toxicity at 1:1 stoichiometry.Soluble in DMSO