CCT241736

Catalog No：GC19092-10mg CAS No.：1402709-93-6 MDLNo： Brand:Glpbio purity： 特性： Purpose:CCT241736 is a potent and orally bioavailable dual FLT3 and Aurora kinase inhibitor, which inhibits Aurora kinases (Aurora-A Kd, 7.5 nM, IC50, 38 nM; Aurora-B Kd, 48 nM), FLT3 kinase (Kd, 6.2 nM), and FLT3 mutants including FLT3-ITD (Kd, 38 nM) and FLT3(D835Y) (Kd, 14 nM).DMSO : 75 mg/mL (164.34 mM; Need ultrasonic);H2O : < 0.1 mg/mL (insoluble)