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PROTAC Sirt2 Degrader-1

Glpbio
Catalog No:GC33418-5mg CAS No.:2098487-75-1 MDLNo: Brand:Glpbio purity: 特性: Purpose:PROTACSirt2Degrader-1是一种基于SirReal的PROTAC,为Sirt2的降解剂,由一个高效、同种型选择性的Sirt2抑制剂,一个连接物和thalidomide(E3泛素化连接酶的配体)组成。PROTACSirt2Degrader-1对Sirt2的IC50值为0.25μM,而对Sirt1/Sirt3(IC50100μM)无作用DMSO : ≥ 100 mg/mL (117.24 mM);H2O : < 0.1 mg/mL (insoluble)
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