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RG-12525 (NID 525)

Glpbio
Catalog No:GC33780-20mg CAS No.:120128-20-3 MDLNo: Brand:Glpbio purity: 特性: Purpose:RG-12525是一种特异性的,竞争性的,可口服的LTC4,LTD4和LTE4拮抗剂,能够抑制LTC4,LTD4和LTE4诱导的豚鼠薄壁带收缩,IC50值分别为2.6nM,2.5nM和7nM;RG-12525也是PPAR-γ的激动剂,IC50值约为60nM,CYP3A4的抑制剂,Ki值为0.5Soluble in DMSO
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