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Pexidartinib hydrochloride

Glpbio

Catalog No：GC34708-50mg CAS No.：2040295-03-0 MDLNo： Brand:Glpbio purity： 特性： Purpose:Pexidartinibhydrochloride(PLX-3397hydrochloride)是一种有效、选择性、ATP-竞争性的CSF1R(cFMS)和c-Kit抑制剂，IC50值分别为20和10nM。Pexidartinib对c-Kit和CSF1R的选择性是对其他相关激酶的10-100倍，例如FLT3，KDR(VEGFR2)，LCK，FLT1(VEGFR1)和NTRK3(TRKC)，IC50值分别为160，350，860，880和890nM。DMSO : 60 mg/mL (132.08 mM; Need ultrasonic)

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Product Overview

Product Name	Pexidartinib hydrochloride
CAS	2040295-03-0
Formula	C₂₀H₁₆Cl₂F₃N₅
MW	454.28
Storage condition	Store at -20°C

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History

Pexidartinib hydrochloride

Pexidartinib hydrochloride

PVR Human