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5-(N,N-Hexamethylene)-amiloride

Glpbio

Catalog No：GC35147-10mg CAS No.：1428-95-1 MDLNo： Brand:Glpbio purity： 特性： Purpose:5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride)，是 amiloride 的衍生物，也是一种有效的 Na+/H+ 交换抑制剂，降低白血病细胞的细胞内 pH (pHi) 并诱导其凋亡。5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) 也是一种 HIV-1 Vpu 病毒离子通道抑制剂，抑制培养在 L929 细胞中的小鼠肝炎病毒 (MHV) 复制和人冠状病毒 229E (HCoV229E) 复制，EC50 值分别为 3.91 μM 和 1.34 μM。DMSO: 100 mg/mL (320.75 mM)

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Product Overview

Product Name	5-(N,N-Hexamethylene)-amiloride
CAS	1428-95-1
Formula	C₁₂H₁₈ClN₇O
MW	311.77
Storage condition	Store at -20°C

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5-(N,N-Hexamethylene)-amiloride

5-(N,N-Hexamethylene)-amiloride