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BMS-906024

Glpbio

Catalog No：GC35535-5mg CAS No.：1401066-79-2 MDLNo： Brand:Glpbio purity： 特性： Purpose:BMS-906024 是一种口服有效，选择性的 γ 分泌酶 (gamma secretase) 抑制剂 (GSI)，GSIs 是一类小分子 Notch 抑制剂。BMS-906024 可阻止具有高口服生物利用度的所有四种 Notch 受体的激活，对于 Notch1，-2，-3 和 -4 受体，IC50s 分别为 1.6，0.7，3.4 和 2.9 nM。 BMS-906024 表现出针对多种人癌症异种移植物的广谱抗肿瘤活性。Soluble in DMSO

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Product Overview

Product Name	BMS-906024
CAS	1401066-79-2
Formula	C₂₆H₂₆F₆N₄O₃
MW	556.5
Storage condition	Store at -20°C

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BMS-906024