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Filibuvir

Glpbio
Catalog No:GC36045-1mg CAS No.:877130-28-4 MDLNo: Brand:Glpbio purity: 特性: Purpose:Filibuvir 是 HCV 非结构性 5B 蛋白 (NS5B) RNA 依赖性的 RNA 聚合酶的有效选择性非核苷抑制剂 (NNI),它在 NS5B 的 “Thumb 2” 口袋中非共价结合。 在体外,filibuvir 与基因型 1 a 和 1 b 复制子等效,EC50 为 59 nM。Soluble in DMSO
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