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GSK3368715

Glpbio
Catalog No:GC36191-1mg CAS No.:1629013-22-4 MDLNo: Brand:Glpbio purity: 特性: Purpose:GSK3368715 (EPZ019997) 是具有口服活性的,可逆的,SAM 非竞争性 I 型蛋白精氨酸甲基转移酶 (PRMTs) 抑制剂 (IC50=3.1 nM (PRMT1), 48 nM (PRMT3), 1148 nM (PRMT4), 5.7 nM (PRMT6), 1.7 nM (PRMT8))。GSK3368715 (EPZ019997) 导致精氨酸甲基化状态的转变,改变了外显子的使用,具有很强的抗癌活性。Soluble in DMSO
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