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SEC inhibitor KL-1

Glpbio

Catalog No：GC38063-25mg CAS No.：900308-84-1 MDLNo： Brand:Glpbio purity： 特性： Purpose:SEC inhibitor KL-1 (KL-1) 是一种拟肽先导化合物，有效的选择性 SEC 抑制剂，通过破坏 SEC 支架蛋白 AFF4 和 P-TEFb 之间的相互作用，导致 Pol II 从启动子近端暂停位点的释放受损并且进行性转录延伸的平均速率降低。SEC inhibitor KL-1 剂量依赖性地抑制 AFF4-CCNT1 相互作用，Ki 值为 3.48 μM。DMSO: 41.67 mg/mL (120.51 mM)

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Product Overview

Product Name	SEC inhibitor KL-1
CAS	900308-84-1
Formula	C₁₈H₁₆ClNO₄
MW	345.78
Storage condition	Store at -20°C

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