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Raphin1 acetate

Glpbio
Catalog No:GC38539-100mg CAS No.:2242616-04-0 MDLNo: Brand:Glpbio purity: 特性: Purpose:Raphin1 acetate 是一种口服生物可利用的,选择性调节性磷酸酶 PPP1R15B (R15B) 抑制剂。Raphin1 acetate 与 R15B-PP1c 全磷酸酶强烈结合 (Kd=33 nM),与 R15A-PP1c 相比,结合 R15B-PP1c 约为其 30 倍的选择性。Raphin1 acetate 穿过血脑屏障,并减少蛋白质错误折叠疾病的小鼠模型中的生物和分子缺陷。DMSO: 41.67 mg/mL (143.13 mM)
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