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IDH889

Glpbio
Catalog No：GC38640-25mg CAS No.：1429179-07-6 MDLNo： Brand:Glpbio purity： 特性： Purpose:IDH889 是一种可口服利用的，脑渗透性的，变构和突变特异性的异柠檬酸脱氢酶 (IDH1) 抑制剂。IDH889 对 IDH1 R132* 突变型具有高效选择性，对 IDH1R132H、IDH1R132C 和 IDH1wt 作用的 IC50 值分别为 0.02 μM, 0.072 μM 和 1.38 μM。IDH889 具有高效的细胞内 2-HG 水平抑制作用，其 IC50 值为 0.014 μM。Soluble in DMSO
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Product Overview
Product Name IDH889
CAS1429179-07-6
FormulaC23H25FN6O2
MW436.48
Storage conditionStore at -20°C
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