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TH-257

Glpbio

Catalog No：GC38860-10mg CAS No.：2244678-29-1 MDLNo： Brand:Glpbio purity： 特性： Purpose:TH-257 是一种有效的 LIMK1 和 LIMK2 抑制剂，对 LIMK1 和 LIMK2 的 IC50 值分别为 84 nM 和 39 nM，是 LIMK1 和 LIMK2 的化学探针。TH-257 是一种变构抑制剂，靶向由 αC 和 DFG-out 构象诱导的结合口袋。TH257 具有极好的选择性，在 1 μM 浓度下未观察到针对更广泛的激酶组的显着活性。DMSO: 250 mg/mL (591.66 mM)

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Product Overview

Product Name	TH-257
CAS	2244678-29-1
Formula	C₂₄H₂₆N₂O₃S
MW	422.54
Storage condition	Store at -20°C

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