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SIAIS178

Glpbio
Catalog No:GC39262-1mg CAS No.:2376047-73-1 MDLNo: Brand:Glpbio purity: 特性: Purpose:SIAIS178 是一种 PROTAC 类的有效的,选择性的 BCR-ABL 降解剂,IC50 为 24 nM。SIAIS178 通过募集 Von Hippel-Lindau (VHL) E3 泛素连接酶来降解 BCR-ABL 蛋白。SIAIS178 具有抗肿瘤活性。DMSO: 300 mg/mL (296.24 mM)
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