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(R)-CR8 trihydrochloride

Glpbio

Catalog No：GC39281-10mg CAS No.：1786438-30-9 MDLNo： Brand:Glpbio purity： 特性： Purpose:(R)-CR8 trihydrochloride (CR8 trihydrochloride) 是 Roscovitine 的第二代类似物，是一种有效的 CDK1/2/5/7/9 抑制剂。(R)-CR8 trihydrochloride 抑制 CDK1/cyclin B (IC50=0.09 μM)、CDK2/cyclin A (0.072 μM)、CDK2/cyclin E (0.041 μM)、CDK5/p25 (0.11 μM)、CDK7/cyclin H (1.1 μM)、CDK9/cyclin T (0.18 μM) 和 CK1δ/ε (0.4 μM)。(R)-CR8 trihydrochloride 诱导细胞凋亡并具有神经保护作用。DMSO: 62.5 mg/mL (115.54 mM)

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Product Overview

Product Name	(R)-CR8 trihydrochloride
CAS	1786438-30-9
Formula	C₂₄H₃₂Cl₃N₇O
MW	540.92
Storage condition	Store at -20°C

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(R)-CR8 trihydrochloride

(R)-CR8 trihydrochloride