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ANI-7

Glpbio
Catalog No:GC39284-100mg CAS No.:931417-26-4 MDLNo: Brand:Glpbio purity: 特性: Purpose:ANI-7 是一种 AhR 途径的激活剂。ANI-7 抑制多种癌细胞的生长,并有选择地抑制 MCF-7 乳腺癌细胞的生长,GI50 为 0.56 μM。ANI-7 通过激活 AhR 途径诱导 CYP1 代谢单加氧酶,并在敏感的乳腺癌细胞系中诱导 DNA 损伤,检查点激酶 (Chk2) 激活,S 期细胞周期停滞和细胞死亡。DMSO: 20.83 mg/mL (79.17 mM)
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