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BTRX-335140

Glpbio

Catalog No：GC39354-10mg CAS No.：2244614-14-8 MDLNo： Brand:Glpbio purity： 特性： Purpose:BTRX-335140 (CYM-53093) 是一种有效且选择性的口服 κ opioid receptor (KOR) 拮抗剂，对 κOR，μOR 和 δOR 具有拮抗剂活性，IC50 值分别为 0.8 nM，110 nM 和 6500 nM。BTRX-335140 在大鼠中具有良好的体外 ADMET 和体内药代动力学特征。BTRX-335140 可以很好地分布到 CNS 中。 ADMET (吸收，分布，代谢，排泄和毒性)。DMSO: 16.67 mg/mL (36.75 mM)

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Product Overview

Product Name	BTRX-335140
CAS	2244614-14-8
Formula	C₂₅H₃₂FN₅O₂
MW	453.55
Storage condition	Store at -20°C

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History

BTRX-335140

Lupeol acetate