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MAC glucuronide phenol-linked SN-38

Glpbio
Catalog No:GC39401-5mg CAS No.:2246380-69-6 MDLNo: Brand:Glpbio purity: 特性: Purpose:MAC glucuronide phenol-linked SN-38 是一种对 pH 敏感的内酯化合物,由 ADC 毒物 SN-38 (DNA 拓扑异构酶 I 抑制剂) 和 MAC 葡糖醛酸苷苯酚组成。MAC glucuronide phenol-linked SN-38 对 L540cy 细胞和 Ramos 细胞具有细胞毒性,IC50 分别为 113 和 67 ng/mL。DMSO: 200 mg/mL (183.31 mM)
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