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TRV-120027 TFA

Glpbio

Catalog No：GC39456-5mg CAS No.： MDLNo： Brand:Glpbio purity： 特性： Purpose:TRV120027 TFA 是血管紧张素 II 受体 1 型 (AT1R) 的 β-arrestin-1 激动剂。TRV120027 TFA 通过阳离子通道亚家族 C3 (TRPC3) 偶联诱导急性儿茶酚胺分泌，促进质膜上 AT1R-β-arrestin-1-TRPC3-PLCγ 形成大分子复合物。TRV120027 TFA 抑制血管紧张素 II 介导的血管收缩并增加心肌细胞的收缩力。TRV120027 TFA有潜力用于急性失代偿性心力衰竭 (ADHF) 的研究。Soluble in DMSO

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Product Overview

Product Name	TRV-120027 TFA
Formula	C₄₅H₆₈F₃N₁₃O₁₂
MW	1040.1
Storage condition	Store at -20°C

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History

TRV-120027 TFA

UC-514321