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AMG 511

Glpbio

Catalog No：GC39695-100mg CAS No.：1253573-53-3 MDLNo： Brand:Glpbio purity： 特性： Purpose:AMG 511 是一个高效、口服有效的 I 类 pan-PI3K 抑制剂,对 PI3Kα, β, δ 和 γ 作用的 Ki 值分别为 4 nM, 6 nM, 2 nM 和 1 nM。AMG 511 减少 p-Akt (Ser473), 体现了它显著抑制了 PI3K 信号。AMG 511 在小鼠胶质母细胞瘤移植瘤模型中具有抗肿瘤活性。Soluble in DMSO

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Product Overview

Product Name	AMG 511
CAS	1253573-53-3
Formula	C₂₂H₂₈FN₉O₃S
MW	517.58
Storage condition	Store at -20°C

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