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(E/Z)-GSK5182

Glpbio
Catalog No:GC39747-5mg CAS No.: MDLNo: Brand:Glpbio purity: 特性: Purpose:(E/Z)-GSK5182 是 (E)-GSK5182 和 (Z)-GSK5182 的消旋体。GSK5182 是一种高效选择性,具有口服活性的 ERRγ 反向激动剂,其 IC50 值为 79 nM。GSK5182 还能增加肝癌细胞中 reactive oxyen species (ROS) 的产生。DMSO: 100 mg/mL (239.50 mM); H2O: < 0.1 mg/mL (insoluble)
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