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Mitoguazone

Glpbio

Catalog No：GC39814-10mg CAS No.：459-86-9 MDLNo： Brand:Glpbio purity： 特性： Purpose:Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) 是一种具有有效抗肿瘤活性的合成多羰基衍生物。Mitoguazone 是一种可透过血脑屏障的竞争性的 S-腺苷-蛋氨酸脱羧酶 (S-adenosyl-methionine decarboxylase) 抑制剂，可破坏多胺的生物合成。Mitoguazone 诱导细胞凋亡 (apoptosis)，可抑制 HIV DNA 整合到单核细胞和巨噬细胞中的细胞 DNA 中。Mitoguazone 具可用于急性白血病，霍奇金淋巴瘤和非霍奇金淋巴瘤的研究。H2O: 50 mg/mL (271.44 mM; ultrasonic and adjust pH to 9 with HCl)

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Product Overview

Product Name	Mitoguazone
CAS	459-86-9
Formula	C₅H₁₂N₈
MW	184.2
Storage condition	Store at -20°C

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