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Fedratinib hydrochloride hydrate

Glpbio

Catalog No：GC60161-1g CAS No.：1374744-69-0 MDLNo：C27H40Cl2N6O4S Brand:Glpbio purity： 特性： Purpose:Fedratinibhydrochloridehydrate(TG-101348hydrochloridehydrate)是一种有效的，选择性的，ATP竞争性和具有口服活性的JAK2抑制剂，对于JAK2和JAK2V617F激酶的IC50均为3nM。Fedratinibhydrochloridehydrate对JAK2的选择性分别比JAK1和JAK3高35倍和334倍。Fedratinibhydrochloridehydrate可诱导癌细胞凋亡(apoptosis)，并可用于骨髓增生性疾病的研究。DMSO: 250 mg/mL (406.09 mM; Need ultrasonic)

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Product Name	Fedratinib hydrochloride hydrate
CAS	1374744-69-0
MW	615.62
MDL	C27H40Cl2N6O4S
Storage condition	Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

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GC60161-1g

Fedratinib hydrochloride hydrate

1374744-69-0