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Prexasertib dimesylate

Glpbio

Catalog No：GC60301-10mg CAS No.：1234015-58-7 MDLNo：C20H27N7O8S2 Brand:Glpbio purity： 特性： Purpose:Prexasertibdimesylate(LY2606368dimesylate)是一种选择性的，ATP竞争性的第二代细胞周期检测点激酶1(CHK1)抑制剂，Ki为0.9nM，IC50为<1nM。Prexasertibdimesylate抑制CHK2(IC50=8nM)和RSK1(IC50=9nM)。Prexasertibdimesylate引起双链DNA断裂和复制突变，导致细胞凋亡(apoptosis)。Prexasertibdimesylate显示有效的抗肿瘤活性。DMSO: 100 mg/mL (179.34 mM; Need ultrasonic); H2O: 50 mg/mL (89.67 mM; Need ultrasonic)

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Product Name	Prexasertib dimesylate
CAS	1234015-58-7
MW	557.6
MDL	C20H27N7O8S2
Storage condition	4°C, stored under nitrogen*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

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GC60301-10mg

Prexasertib dimesylate

1234015-58-7