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Vimirogant hydrochloride

Glpbio
Catalog No:GC60380-5mg CAS No.: MDLNo:C27H35F3N4O3S.xHCl Brand:Glpbio purity: 特性: Purpose:Vimirogant(VTP-43742)hydrochloride是一种选择性、具有口服活性的的RORγt抑制剂(Ki=3.5nM;IC50=17nM)。Vimiroganthydrochloride与RORα和RORβ比,高出1000倍的选择性。Vimiroganthydrochloride抑制小鼠脾细胞的Th17分化和IL-17A分泌(IC50=57nM),而不会影响Th1,Th2或Treg细胞的分化。Vimiroganthydrochloride可用于研究自身免疫性疾病研究。DMSO: 125 mg/mL (Need ultrasonic)
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Product Overview
Product Name Vimirogant hydrochloride
MDLC27H35F3N4O3S.xHCl
Storage conditionPowder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
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