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CL2A-SN-38

Glpbio

Catalog No：GC60714-5mg CAS No.：1279680-68-0 MDLNo：C73H97N11O22 Brand:Glpbio purity： 特性： Purpose:CL2A-SN-38是drug-linkerconjugate，由linkerCL2A和毒性分子SN-38连接而成的，可用来制备抗体偶联药物。CL2A-SN-38针对人类实体瘤表现出特异性的抗肿瘤作用。SN-38是一种DNATopoisomeraseI抑制剂。CL2A是一种不可降解(non-cleavable)的含PEG8-和三偶氮的PBC-肽-mclinker。CL2A通过pH敏感性降解，产生旁观者效应，并通过二硫键与抗体结合在半胱氨酸残基上。DMSO: 100 mg/mL (67.54 mM; Need ultrasonic)

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Product Overview

Product Name	CL2A-SN-38
CAS	1279680-68-0
MW	1480.61
MDL	C73H97N11O22
Storage condition	-20°C, stored under nitrogen, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

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GC60714-5mg

CL2A-SN-38

1279680-68-0