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Finerenone

Glpbio
Catalog No:GC60842-5mg CAS No.:1050477-31-0 MDLNo:C21H22N4O3 Brand:Glpbio purity: 特性: Purpose:Finerenone(BAY94-8862)是第三代选择性、具有口服活性的、非甾体类盐皮质激素受体(MR)拮抗剂(IC50=18nM)。与糖皮质激素受体(GR)、雄激素受体(AR)和孕酮受体(AR)相比,Finerenone表现出良好的选择性(500-fold)。Finerenone在心肾疾病研究中具有潜在的应用前景,如2型糖尿病和慢性肾脏疾病。
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