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KB02-JQ1

Glpbio
Catalog No:GC60964-10mg CAS No.:2384184-44-3 MDLNo:C38H43Cl2N7O6S Brand:Glpbio purity: 特性: Purpose:KB02-JQ1是一种高选择性的基于PROTAC的BRD4降解剂(molecularglue),但不降解BRD2或BRD3。KB02-JQ1通过共价修饰DCAF16(E3ligase)促进BRD4降解,并可以提高生物系统中蛋白质降解的持久性。KB02-JQ1由JQ1与泛素E3连接酶配体(KB02)通过linker连接而成。DMSO: 200 mg/mL (251.02 mM; Need ultrasonic); H2O: < 0.1 mg/mL (insoluble)
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Product Overview
Product Name KB02-JQ1
CAS2384184-44-3
MW796.76
MDLC38H43Cl2N7O6S
Storage conditionPowder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
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