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KRAS inhibitor-9

Glpbio

Catalog No：GC60969-25mg CAS No.：300809-71-6 MDLNo：C13H9ClN2S2 Brand:Glpbio purity： 特性： Purpose:KRASinhibitor-9是有效的KRAS抑制剂(Kd=92μM)，阻止GTP-KRAS的形成和KRAS下游激活。KRASinhibitor-9以中等的结合亲和力与KRASG12D，KRASG12C和KRASQ61H蛋白结合。KRASinhibitor-9导致G2/M细胞周期停滞并诱导凋亡(apoptosis)。KRASinhibitor-9选择性抑制具有KRAS突变的NSCLC细胞的增殖，但不抑制正常肺细胞的增殖。KRASinhibitor-9DMSO: 250 mg/mL (853.80 mM; Need ultrasonic)

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Product Overview

Product Name	KRAS inhibitor-9
CAS	300809-71-6
MW	292.81
MDL	C13H9ClN2S2
Storage condition	Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

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GC60969-25mg

KRAS inhibitor-9

300809-71-6