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Vercirnon sodium

Glpbio
Catalog No:GC61372-10mg CAS No.:886214-18-2 MDLNo:C22H20ClN2NaO4S Brand:Glpbio purity: 特性: Purpose:Vercirnon(GSK-1605786)sodium是一种具有口服活性的,选择性的CCR9拮抗剂。Vercirnonsodium抑制CCR9介导的Molt-4细胞上Ca2+移动和趋化性,IC50值分别为5.4和3.4nM。Vercirnonsodium对CCR9的选择性高于CCR1-12和CX3CR1-7(IC50s=10µM)。Vercirnonsodium是CCR9的两种剪接形式(CCR9A和CCR9B)的CCL25定向趋化性的等效抑制剂,IC50值分别为2.8和2.6nM。DMSO: 100 mg/mL (214.17 mM; Need ultrasonic)
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Product Overview
Product Name Vercirnon sodium
CAS886214-18-2
MW466.91
MDLC22H20ClN2NaO4S
Storage condition4°C, stored under nitrogen *In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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