Home > Category > Pactimibe

Pactimibe

Glpbio

Catalog No：GC61631-5mg CAS No.：189198-30-9 MDLNo：C25H40N2O3 Brand:Glpbio purity： 特性： Purpose:Pactimibe(CS-505freebase)是一种ACAT1/2双重抑制剂，对于ACAT1的IC50值为4.9μM，对于ACAT2的IC50值为3.0μM。Pactimibe(CS-505freebase)抑制ACAT，其IC50值在肝细胞中是2.0μM，在巨噬细胞中是2.7μM，在THP-1细胞中是4.7μM。Pactimibe(CS-505freebase)非竞争性抑制oleoyl-CoA，Ki是5.6μM。此外，Pactimibe(CS-505freebase)明显抑制胆固醇酯的形成，IC50是6.7μM。Pactimibe(CS-505freebase)具有抗动脉粥样硬化的潜力，可降低血浆胆固醇的活性。DMSO: 200 mg/mL (480.08 mM; Need ultrasonic)

Size	Availability	Price(USD)
There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Chemical safety data sheet(MSDS)

Download MSDS

Inquiry

Product Overview
Related documents
Related literature

Product Overview

Product Name	Pactimibe
CAS	189198-30-9
MW	416.6
MDL	C25H40N2O3
Storage condition	4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)