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PIN1 inhibitor API-1

Glpbio

Catalog No：GC38036-100mg CAS No.：680622-70-2 MDLNo： Brand:Glpbio purity： 特性： Purpose:PIN1 inhibitor API-1 是一种特殊的 Pin1 (peptidyl-prolyl cis-trans isomerase NIMA-interacting 1) 抑制剂 (API-1)，IC50 为 72.3 nM。PIN1 inhibitor API-1 直接特异性地与 Pin1 肽基脯氨酰异构酶 (PPIase) 结构域结合，并抑制 Pin1 顺反异构活性。PIN1 inhibitor API-1 保留 pXPO5 的活性构象，恢复 pXPO5 将前 miRNA 从细胞核转运到细胞质的能力，从而上调抗癌 miRNA 的生物发生，抑制体外和体内肝癌的发生。DMSO: 250 mg/mL (682.50 mM)

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Product Overview

Product Name	PIN1 inhibitor API-1
CAS	680622-70-2
Formula	C₁₅H₁₅F₃N₆O₂
MW	368.31
Storage condition	Store at -20°C

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PIN1 inhibitor API-1

PIN1 inhibitor API-1

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HU IL-1 B RECOMB

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