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Glpbio

(Gly²¹)-Amyloid β-Protein (1-40)

产品编号:GA20197-1mg CAS No.:154362-03-5 品牌:Glpbio 等级: 特性: 用途:Contrary to β-amyloid peptides mutated at position 22 (Dutch, Italian, Arctic mutants) the Flemish mutation (A21G) shows a decreased tendency to aggregate and a reduced neurotoxicity. In the studies of Betts and Tsubuki, A21G was degraded significantly more slowly by neprilysin than the wild-type Aβ 1-40 and the E22 mutants. The relative resistance to proteolytic degradation may account for the pathogenicity of the Aβ mutant.Soluble in DMSO
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